Hypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis

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Hypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis.

Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...

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Hypercalcaemia Associated with Neonatal Subcutaneous Fat Necrosis By

Localized neonatal subcutaneous fat necrosis has been well recognized since the description of Fabyan (1907). Since then many case reports have been published: thus Masi and Brancolini (1956) collected 179 reported cases. Calcium deposition in affected tissues was described by Harrison and McNee (1926) and a raised serum calcium was reported in one of their cases. The association of this condit...

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Zoledronic acid for neonatal subcutaneous fat necrosis

Subcutaneous fat necrosis (SFN) in infants producing severe hypercalcemia is a life-threatening emergency. Pathophysiology may include enhanced gastrointestinal calcium absorption and bone resorption. We treated an infant with SFN and serum calcium of 15 mg/dL with prednisolone and low-dose zoledronic acid. Serum calcium promptly normalized without rebound hypocalcemia, and redosing of zoledron...

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Bone scanning in neonatal subcutaneous fat necrosis.

abscesses—particularly subdiaphragmatic—are difficult to detect utilizing this modality. In ultrasonography on the other hand, the presence of the liver is quite useful, for it dis places bowel that might otherwise block sound transmission due to its gas content, and thus renders this area ideal for ultrasonic search. Similarly, in the pelvis, the presence of a filled bladder allows detaile...

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Subcutaneous fat necrosis with hypercalcemia.

We report the case of an infant with diffuse subcutaneous fat necrosis following birth asphyxia who had hypercalcemia and the rare complication of venous calcification. The clinical and radiologic findings resolved over 5 months. The disease is characterized by the presence of painless subcutaneous nodules, mainly over bony prominences, possibly associated with hypercalcemia and calcification. ...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1963

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.38.201.516